Apresentação

O LabMeeb possui duas linhas de pesquisa principais como maneira de aprimoramento do estudo de catalise enzimática e sua utilização em reações de interesse para a sociedade. A primeira linha de pesquisa esta voltada para a imobilização de enzimas em nanopartículas magnéticas como forma de reutilizar e estabilizar os biocatalisadores. A segunda linha de pesquisa esta voltada para o uso dos sítios ativos de metaloenzimas como fonte de inspiração para o desenho de novos complexos metálicos catalíticos.

Publicações

  • Ferreira, M.P, Castro, C.B., Honorato, J., He, S., Guimaraes Junior, W.G., Esmieu, C., Castellano, E.E., Moura, A.F., Truzzi, D.R., Nascimento, O. R., Simonneau, A., Marques Netto, C.G.C. Biomimetic catalysis of nitrite reductase enzyme using copper complexes in chemical and electrochemical reduction of nitrite. Dalton Trans. 2023, accepted.
  • Martins, C.O.; Sebastiany, L.K.; Lopez-Castillo, A.; Freitas, R.S.; Andrade, L.H.; Toma, H.E.; Netto, C.G.C.M. Urea Decomposition Mechanism by Dinuclear Nickel Complexes. Molecules 2023, 28, 1659
  • Marques Netto, C.G.C., Board Game-based online methodology improves student´s learning and sense of well-being during the COVID-19 pandemic, Chem. Educ., 2022, 99,6,2310
  • Castro, C.B., Ferreira, M.P., Marques Netto, C.G.C., Metalloenzyme mechanisms correlated to their turnover number and metal lability, Res. Chem. Biol., 2021, 1, 100004
  • Castro, C.B., Teixeira, I.V., Marques Netto, C.G.C, Periodic Trends in a Simulated Water Treatment Station: A methodology to Engage Students in the Lower Levels of Inorganic Chemistry Learning, Chem. Educ., 2020, 97, 8, 2175
  • Castro, C.B., Silveira, R.G., Colombari, F.M., Moura, A.F., Nascimento, O.R., Marques Netto, C.G.C., Solvent Effect on the Regulation of Urea Hydrolysis Reactions by Copper Complexes, Chemistry, 2020, 2(2), 525
  • Sastre, D.E., Pulschen, A.A., Basso, L.G.M., Benites, Pariente J.S., Marques Netto, C.G.C., Machinandiarena, F., Albanesi, D., Navarro, M.V.A.S., de Mendoza, D., Gueiros-Filho, F., The phosphatidic-acid pathway enzyme PlsX plays both catalytic and channeling roles in bacterial phospholipid synthesis, J. Biol. Chem., 2020, 295, 7, 2148
  • Sastre, D.E., Reis, E.A., Marques Netto, C.G.C., Strategies to rationalize enzyme immobilization procedures, Methods in Enzymology, 2020, 630,81
  • Modenez, I.; Sastre, D; Moraes, F.C; Marques Netto, C.G.C.. Influence of Glutaraldehyde Cross-Linking Modes on the Recyclability of Immobilized Lipase B from Candida antarctica for Transesterification of Soy Bean Oil. Molecules, 2018, 23, p. 2230.
  • Marques Netto, C.G.C, Palmeira, D.J., Brondani, P.B., Andrade, L.H., Enzymatic reactions involving the heteroatoms from organic substrates. ANAIS DA ACADEMIA BRASILEIRA DE CIÊNCIAS (ONLINE), 2018 ,90, p. 943-992.
  • Marques Netto, C.G.C., Andrade, L.H., Toma, H.E., Carbon dioxide/methanol conversion cycle based on cascade enzymatic reactions supported on superparamagnetic nanoparticles. ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS, 2017, 90, 593-606.
  • Marques Netto, C.G.C., da Silva, D.G., Toma, S.H., Andrade L.H., Nakamura, M., Araki, K., Toma, H.E., Bovine glutamate dehydrogenase immobilization on magnetic nanoparticles: conformational changes and catalysis. RSC Advances, 2016, 6, 12977-12992.
  • Toma, H.E., Andrade, M.F.C., Parussulo, A.L.A., Marques Netto, C.G.C., Andrade, L.H., Lipase immobilized on polydopamine-coated magnetite nanoparticles for biodiesel production from soybean oil. Biofuel Research Journal, 2016, 3, 403-409.
  • Marques Netto, C.G.C., Andrade L.H., Toma, H.E., Association of Pseudomonas putida formaldehyde dehydrogenase with superparamagnetic nanoparticles: an effective way of improving the enzyme stability, performance and recycling. New Journal of Chemistry, 2015, 39, 2162-2167.
  • Marques Netto, C.G.C., Andrade, L.H., Freitas, R.S., Toma, H.E., Association of yeast alcohol dehydrogenase with superparamagnetic nanoparticles: improving the enzyme stability and performance. Journal of Nanoscience and Nanotechnology (Print), 2014, 15, 12, 9482
  • Marques Netto, C.G.C., Toma, H.E., CO2 Complexation and Activation by a Trost-Bis(ProPhenol)Cobalt Complex. European Journal of Inorganic Chemistry, 2013, 34, p. 5826-5830
  • Marques Netto, C.G.C., Toma, H.E, Andrade, L.H., Superparamagnetic nanoparticles as versatile carriers and supporting materials for enzymes. Journal of Molecular Catalysis B: Enzymatic, 2013, 85-86, p. 71-92
  • Marques Netto, C.G.C., Nakamura, M., Andrade, L.H., Toma, H.E., Improving the catalytic activity of formate dehydrogenase from Candida Boidinii by using magnetic nanoparticles. Journal of Molecular Catalysis B: Enzymatic, 2012, 84, p. 136-143
  • Marques Netto, C.G.C., Nakamatsu, E.H., Netto, L.E.S., Novak, M.A., Zuin, A., Nakamura, M., Araki, K., Toma, H.E., Catalytic properties of thioredoxin immobilized on superparamagnetic nanoparticles. Journal of Inorganic Biochemistry, 2011, 105, p. 738-744
  • Andrade, L.H., Rebelo, L., Marques Netto, C.G.C., Toma, H.E., Kinetic resolution of a drug precursor by Burkholderia cepacia lipase immobilized. Journal of Molecular Catalysis. B, Enzymatic, 2010, v. 66, p. 55-62.
  • Rebelo, L. Marques Netto, C.G.C., Andrade, L.H., Toma, H.E. Enzymatic Kinetic Resolution of (RS)-1-(Phenyl)ethanols by Burkholderia cepacia Lipase Immobilized on Magnetic Nanoparticles. Journal of the Brazilian Chemical Society (Online), 2010, 21, p. 1537-1542.
  • Marques Netto, C.G.C., Andrade, L.H., Toma, H.E., Enantioselective transesterification catalysis by Candida antarctica lipase. Asymmetry, 2009, 20, p. 2299-2304.